Düzyatan was born in Izmir, Turkey. Engin Altan Düzyatan began acting during his high school days. He joined Dokuz Eylül University to study theatre. He completed his course and moved to İstanbul where he started his professional acting career.
He made his screen debut in the television series Ruhsar and went on to appear in Yeditepe İstanbul, Koçum Benim and Alacakaranlık. In 2005, he acted in the films Beyza’nın Kadınları directed by Mustafa Altıoklar and Kalbim Zamanı. In 2007, Düzyatan appeared in the series Sevgili Dünürüm with Haluk Bilginer, Sumru Yavrucuk and Nevra Serezli. His next roles were in the films Cennet (2008) and Mezuniyet (2009). In 2009, he played Doctor Serdar Batur in the series Bir Bulut Olsam with Melisa Sözen and Engin Akyürek, written by Meral Okay.
Düzyatan acted in the films Romantik Komedi, New York’ta Beş Minare and Bir Avuç Deniz in 2010.
He hosted the game show Canlı Para which is Turkish version of The Million Pound Drop Live on Show TV in 2010 and 2011.
He has a new series in Kanal D titled, Cinayet. His co-actors are Nurgül Yeşilçay, Uğur Polat, Şükran Ovalı, Ahmet Mümtaz Taylan and Goncagül Sunar.
From 2014 until presently, he has starred in the TV series named Diriliş: Ertuğrul in its namesake leading role on TRT 1.